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Article

Using Nature's "Tricks" To Rationally Tune the Binding Properties of Biomolecular Receptors.

Accounts of chemical research - 20 Sept 2016

Ricci Francesco, Vallée-Bélisle Alexis, Simon Anna J, Porchetta Alessandro, Plaxco Kevin W

Abstract excerpt

The biosensor community has long focused on achieving the lowest possible detection limits, with specificity (the ability to differentiate between closely similar target molecules) and sensitivity (the ability to differentiate between closely similar target concentrations) largely being relegated to secondary considerations and solved by the inclusion of cumbersome washing and dilution steps or via careful...

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Identifiers

PMID: 27564548
DOI: 10.1021/acs.accounts.6b00276
PMCID: PMC5660318

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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