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Article

TP53 codon 72 polymorphism may predict early tumour progression in paediatric pilocytic astrocytoma.

Oncotarget - 26 Jul 2016

Mascelli Samantha, Nozza Paolo, Jones David T W, Colin Carole, Pistorio Angela, Milanaccio Claudia, Ravegnani Marcello, Consales Alessandro, Witt Olaf, Morana Giovanni, Cama Armando, Capra Valeria, Biassoni Roberto, Pfister Stefan M, Figarella-Branger Dominique, Garrè Maria Luisa, Raso Alessandro

Abstract excerpt

Pilocytic astrocytoma and ganglioglioma may occur in inaccessible or surgically difficult areas. In case of incomplete resection, the availability of biological predictors of tumour progression could be particularly important. To this end, an analysis of p53 codon 72 polymorphism and assessment of its role as prognostic marker were performed.The status of the p53 Arg72Pro polymorphism was evaluated by...

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Identifiers

PMID: 27374106
DOI: 10.18632/oncotarget.10295
PMCID: PMC5216988

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Source receipt: pubmed, retrieved 7 Sept 2026.

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