Article
TP53 polymorphisms in gliomas from Indian patients: Study of codon 72 genotype, rs1642785, rs1800370 and 16 base pair insertion in intron-3.
Experimental and molecular pathology - 1 Apr 2011
Jha Prerana, Jha Pankaj, Pathak Pankaj, Chosdol Kunzang, Suri Vaishali, Sharma Mehar Chand, Kumar Guresh, Singh Manmohan, Mahapatra Ashok Kumar, Sarkar Chitra
Abstract excerpt
Several single nucleotide polymorphisms of the TP53 gene have been reported, amongst which polymorphism in codon 72 (rs1042522) has received significant attention and shown to be associated with disease susceptibility in different cancer types. However, there are variable reports on this polymorphism in gliomas from worldwide with inconsistent results. In addition, the implications of other polymorphic loci are...
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