Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pilocytic astrocytoma in adults: Histopathological, immunohistochemical and molecular study with clinical association.

Pathology, research and practice - 1 Dec 2023

Salles Débora, Santino Samara F, Diana Paula, Malinverni Andréa C M, Stávale João N

Abstract excerpt

Pilocytic astrocytoma is the most common primary CNS neoplasm in children and adolescents, rare after the first two decades of life. While some authors report a favorable prognosis in the adult age group with the tumor, others have associated it with higher mortality. The molecular alteration most observed in cases of pilocytic astrocytoma in the pediatric group is the BRAF-KIAA1549 gene fusion, and there are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Astrocytoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain Neoplasms

Share to Mutation

Share to Oncogene Proteins, Fusion

Share to Proto-Oncogene Proteins B-raf

Source

Identifiers

PMID: 37984046
DOI: 10.1016/j.prp.2023.154942

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pilocytic astrocytoma in adults: Histopathological, immunohistochemical and molecular study with clinical association.PMID 37984046Read ↗

Pilocytic astrocytoma: pathology, molecular mechanisms and markers.Semantic proximity Read ↗

Adult pilocytic astrocytoma in the molecular era: a comprehensive reviewSemantic proximity Read ↗

KIAA1549: BRAF Gene Fusion and FGFR1 Hotspot Mutations Are Prognostic Factors in Pilocytic Astrocytomas.Semantic proximity Read ↗

The involvement of the MAPK pathway in pilocytic astrocytomas.Semantic proximity Read ↗

Pilocytic astrocytoma harboring a novel GNAI3-BRAF fusion.Semantic proximity Read ↗

Integrating Molecular Analyses with the 2021 WHO Classification for a More Precise Diagnosis of Adult Pilocytic AstrocytomasSemantic proximity Read ↗

V600E BRAF mutation in pilocytic astrocytoma is associated with a more diffuse growth pattern but does not confer a more aggressive clinical behavior.Semantic proximity Read ↗

Adult pilocytic astrocytomas: clinical features and molecular analysis.Semantic proximity Read ↗

A new GTF2I-BRAF fusion mediating MAPK pathway activation in pilocytic astrocytomaSemantic proximity Read ↗

The differential diagnosis of pilocytic astrocytoma with atypical features and malignant glioma: an analysis of 16 cases with emphasis on distinguishing molecular features.Semantic proximity Read ↗

BRAF alterations in primary glial and glioneuronal neoplasms of the central nervous system with identification of 2 novel KIAA1549:BRAF fusion variants.Semantic proximity Read ↗

The histomolecular criteria established for adult anaplastic pilocytic astrocytoma are not applicable to the pediatric populationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.