IRF-3 gene polymorphisms are associated with the susceptibility to and the survival in chronic lymphocytic leukemia and could also serve as an auxiliary index.

doi:10.1080/10428194.2016.1193858

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Article

IRF-3 gene polymorphisms are associated with the susceptibility to and the survival in chronic lymphocytic leukemia and could also serve as an auxiliary index.

Leukemia & lymphoma - 1 Mar 2017

Zhang Zong-Xin, Shen Cui-Fen, Shou Li-Hong, Fang Qiu

Abstract excerpt

The objective of this article was to investigate the relationship between IRF-3 gene polymorphisms and the susceptibility and prognosis of CLL. Between January 2011 and August 2012, 108 CLL patients and 112 healthy were enrolled in the study. DHPLC and Shesis software were applied in our study. In rs7251, CG genotype may increase the CLL risk. In the rs2304206, the alleles T may increase the CLL risk. The GTC...

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PMID: 27348780
DOI: 10.1080/10428194.2016.1193858

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