Article
Genetic susceptibility variants for chronic lymphocytic leukemia.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2010
Slager Susan L, Goldin Lynn R, Strom Sara S, Lanasa Mark C, Spector Logan G, Rassenti Laura, Leis Jose F, Camp Nicola J, Kay Neil E, Vachon Celine M, Glenn Martha, Weinberg J Brice, Rabe Kari G, Cunningham Julie M, Achenbach Sara J, Hanson Curtis A, Marti Gerald E, Call Timothy G, Caporaso Neil E, Cerhan James R
Abstract excerpt
BACKGROUND: There is strong and consistent evidence that a genetic component contributes to the etiology of chronic lymphocytic leukemia (CLL). A recent genome-wide association study of CLL identified seven genetic variants that increased the risk of CLL within a European population. METHODS: We evaluated the association of these variants, or variants in linkage disequilibrium with these variants, with CLL risk...
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