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Article

NOTCH1 and SF3B1 mutations in chronic lymphocytic leukemia with their clinical associations.

Leukemia & lymphoma - 1 Apr 2026

Ahmed Vanya Rashid, Rahman Fryad Majeed

Abstract excerpt

Chronic lymphocytic leukemia (CLL) exhibits heterogeneous clinical outcomes influenced by chromosomal aberrations and genetic mutations. NOTCH1 and SF3B1 mutations are critical prognostic markers linked to disease progression and therapy resistance. This study analyzed 60 CLL patients from Hiwa Hospital (Sulaymaniyah, Iraq). Hematological parameters were assessed, and genomic DNA was sequenced for NOTCH1 exon 34...

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Share to Aged, 80 and over
Share to DNA Mutational Analysis
Share to Leukemia, Lymphocytic, Chronic, B-Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Staging

Share to Phosphoproteins

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Share to Receptor, Notch1

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Source

Identifiers

PMID: 41689380
DOI: 10.1080/10428194.2026.2626937

Genes

NOTCH1
SF3B1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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