Article
Prognostic impact of NOTCH1, MYD88, and SF3B1 mutations in Polish patients with chronic lymphocytic leukemia.
Polish archives of internal medicine - 28 Apr 2017
Putowski Maciej, Podgórniak Marta, Piróg Marta, Knap Joanna, Zaleska Joanna, Purkot Joanna, Zawiślak Jacek, Zakrzewska Ewelina, Karczmarczyk Agnieszka, Własiuk Paulina, Subocz Edyta, Giannopoulos Krzysztof
Abstract excerpt
INTRODUCTION Currently available prognostic factors determining the course of chronic lymphocytic leukemia (CLL) are not fully efficient, especially for newly diagnosed patients. Investigation of molecular changes may help clarify the reasons for the heterogeneity of the disease. Apart from already confirmed TP53 mutations, the novel candidates: NOTCH1, SF3B1, and MYD88 might represent clinically relevant...
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