Article
Genetic susceptibility for chronic lymphocytic leukemia among Chinese in Hong Kong.
European journal of haematology - 1 Dec 2010
Lan Qing, Au Wing-Yan, Chanock Stephen, Tse Jovic, Wong Kit-fai, Shen Min, Siu L P, Yuenger Jeff, Yeager Meredith, Hosgood Howard Dean, Purdue Mark P, Liang Raymond, Rothman Nathaniel
Abstract excerpt
The genetic basis of chronic lymphocytic leukemia (CLL) has not been fully elucidated to date. Although it is the most common haematological malignancy in Caucasians, it is uncommon among Asians. A recent genome-wide scan of CLL in Caucasians, which was carried out in the UK, identified six variants showing strong association. We attempted to replicate these findings in 71 patients with CLL and 1273 controls in...
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