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Article

Tau-positive nuclear indentations in P301S tauopathy mice.

Brain pathology (Zurich, Switzerland) - 1 May 2017

Fernández-Nogales Marta, Santos-Galindo María, Merchán-Rubira Jesús, Hoozemans Jeroen J M, Rábano Alberto, Ferrer Isidro, Avila Jesús, Hernández Félix, Lucas José J

Abstract excerpt

Increased incidence of neuronal nuclear indentations is a well-known feature of the striatum of Huntington's disease (HD) brains and, in Alzheimer's disease (AD), neuronal nuclear indentations have recently been reported to correlate with neurotoxicity caused by improper cytoskeletal/nucleoskeletal coupling. Initial detection of rod-shaped tau immunostaining in nuclei of cortical and striatal neurons of HD brains...

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Identifiers

PMID: 27338164
DOI: 10.1111/bpa.12407
PMCID: PMC8029483

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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