Article

Pathological α-Synuclein Perturbs Nuclear Integrity

2025-03-10

Abstract excerpt

Pathological aggregates of α-synuclein are a hallmark of a group of neurodegenerative disorders collectively termed synucleinopathies. The physiological function of α-synuclein, and the detrimental effects of the pathological variants of α-synuclein have been widely debated, but recent evidence has suggested an emerging consensus on a critical role for α-synuclein in regulating synaptic function. However, a contro...

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Literature Corpus work: f57509f3-ba97-5e53-8789-c2c113fb5294
DOI: 10.1101/2025.03.04.641384

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