Article
Correlating blood levels of 8-hydroxydeoxyguanosine to hOGG1 genotypes and the incidence of ischemic cardiomyopathy.
The Kaohsiung journal of medical sciences - 1 May 2016
Jin Yu, Qiu Chun-Guang, Zheng Qiang-Sun, Ding Shi-Fang, Jiang Qi-Jun
Abstract excerpt
We measured the serum levels of 8-hydroxydeoxyguanosine (8-OHdG) and investigated whether these levels correlate with incidence of ischemic cardiomyopathy (ICM), and whether these levels correlate with underlying oxidative stress in patients with ICM. Polymerase chain reaction-restriction fragment length polymorphism analysis was performed to assess the prevalence of the Ser/Cys polymorphism in the human...
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