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The 8-oxoguanine glycosylase I (hOGG1) Ser326Cys variant affects the susceptibility to multi-vessel disease in Taiwan coronary artery disease patients.

Thrombosis research - 1 Oct 2010

Wang Chiao-Ling, Lin Tsung-Hsien, Lin Hsing-Yi, Sheu Sheng-Hsiung, Yu Ming-Lung, Hsiao Pi-Jung, Lin Kun-Der, Hsu Chin, Yang Yi-Hsin, Shin Shyi-Jang

Abstract excerpt

8-hydroxydeoxyguanosine, the key lesion of oxidative DNA damage, contributes to the development of coronary artery disease (CAD). In humans, 8-hydroxydeoxyguanosine is repaired by the enzyme 8-oxoguanine glycosylase I (hOGG1). We investigated the association between the hOGG1 Ser(326)Cys polymorp...

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Source

Identifiers

PMID: 20667409
DOI: 10.1016/j.thromres.2010.06.021

Genes

CAD
MVD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20667409-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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