Article
mTOR pathway candidate genes and physical activity interaction on breast cancer risk in black women from the women's circle of health study.
Breast cancer research and treatment - 1 May 2023
Ilozumba Mmadili N, Yaghjyan Lusine, Datta Susmita, Zhao Jinying, Gong Zhihong, Hong Chi-Chen, Lunetta Kathryn L, Zirpoli Gary, Bandera Elisa V, Palmer Julie R, Yao Song, Ambrosone Christine B, Cheng Ting-Yuan David
Abstract excerpt
BACKGROUND: Physical activity has been shown to affect the mammalian target of rapamycin (mTOR) signaling pathway and consequently breast carcinogenesis. Given that Black women in the USA are less physically active, it is not well understood whether there are gene-environment interactions between mTOR pathway genes and physical activity in relation to breast cancer risk in Black women. METHODS: The study included...
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