Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3' untranslated region.

Genome biology - 31 Oct 2022

Fernández Lara P, Deleyto-Seldas Nerea, Colmenarejo Gonzalo, Sanz Alba, Wagner Sonia, Plata-Gómez Ana Belén, Gómez-Patiño Mónica, Molina Susana, Espinosa-Salinas Isabel, Aguilar-Aguilar Elena, Ortega Sagrario, Graña-Castro Osvaldo, Loria-Kohen Viviana, Fernández-Marcos Pablo J, Efeyan Alejo, Ramírez de Molina Ana

Abstract excerpt

BACKGROUND: Overweight and obesity are defined by an anomalous or excessive fat accumulation that may compromise health. To find single-nucleotide polymorphisms (SNPs) influencing metabolic phenotypes associated with the obesity state, we analyze multiple anthropometric and clinical parameters in a cohort of 790 healthy volunteers and study potential associations with 48 manually curated SNPs, in metabolic genes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Carrier Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MicroRNAs

Share to Obesity

Share to Overweight

Share to RNA, Messenger

Share to Thinness

Source

Open in PubMed Open full text

Identifiers

PMID: 36316722
DOI: 10.1186/s13059-022-02798-5
PMCID: PMC9620695

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3' untranslated region.PMID 36316722Read ↗

Genetic association and gene expression analysis identify FGFR1 as a new susceptibility gene for human obesity.Semantic proximity Read ↗

FTO Gene Affects Obesity and Breast Cancer Through Similar Mechanisms: A New Insight into the Molecular Therapeutic TargetsSemantic proximity Read ↗

Identification and characterization of the long non-coding RNA NFIA-AS2 as a novel locus for body mass index in American Indians.Semantic proximity Read ↗

A genomics perspective of personalized prevention and management of obesitySemantic proximity Read ↗

Association of Mutations in the Melanocortin-2 Receptor Accessory Protein 2 Gene (MRAP2) and Obesity: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

FTO – A Common Genetic Basis for Obesity and CancerSemantic proximity Read ↗

Four-and-a-half LIM domain protein 2 (FHL2) deficiency protects mice from diet-induced obesity and high FHL2 expression marks human obesity.Semantic proximity Read ↗

Genetic variants of LEAP2 are associated with anthropometric traits and circulating insulin-like growth factor-1 concentration: A UK Biobank study.Semantic proximity Read ↗

Assessing the effects of 35 European-derived BMI-associated SNPs in Mexican children.Semantic proximity Read ↗

Genomic variants at 20p11 associated with body fat mass in the European population.Semantic proximity Read ↗

FTO associations with obesity and telomere length.Semantic proximity Read ↗

Integrated miRNA–mRNA Analysis Reveals Dysregulated Regulatory Networks in Visceral Adipose Tissue Linked to Obesity and Type 2 DiabetesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.