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Article

Association of breast cancer risk and the mTOR pathway in women of African ancestry in 'The Root' Consortium.

Carcinogenesis - 1 Aug 2017

Wang Shengfeng, Huo Dezheng, Ogundiran Temidayo O, Ojengbede Oladosu, Zheng Wei, Nathanson Katherine L, Nemesure Barbara, Ambs Stefan, Olopade Olufunmilayo I, Zheng Yonglan

Abstract excerpt

Functional studies have elucidated the role of the mammalian target of rapamycin (mTOR) pathway in breast carcinogenesis, but to date, there is a paucity of data on its contribution to breast cancer risk in women of African ancestry. We examined 47628 SNPs in 61 mTOR pathway genes in the genome wide association study of breast cancer in the African Diaspora study (The Root consortium), which included 3686...

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Identifiers

PMID: 28582508
DOI: 10.1093/carcin/bgx055
PMCID: PMC5862308

Genes

PRKAG3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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