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Article

mTOR pathway candidate genes and obesity interaction on breast cancer risk in black women from the Women's Circle of Health Study.

Cancer causes & control : CCC - 1 May 2023

Ilozumba Mmadili N, Yaghjyan Lusine, Datta Susmita, Zhao Jinying, Hong Chi-Chen, Lunetta Kathryn L, Zirpoli Gary, Bandera Elisa V, Palmer Julie R, Yao Song, Ambrosone Christine B, Cheng Ting-Yuan David

Abstract excerpt

BACKGROUND: Obesity is known to stimulate the mammalian target of rapamycin (mTOR) signaling pathway and both obesity and the mTOR signaling pathway are implicated in breast carcinogenesis. We investigated potential gene-environment interactions between mTOR pathway genes and obesity in relation to breast cancer risk among Black women. METHODS: The study included 1,655 Black women (821 incident breast cancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36790512
DOI: 10.1007/s10552-022-01657-9
PMCID: PMC10695180

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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