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Article

mTOR pathway candidate genes and energy intake interaction on breast cancer risk in Black women from the Women's Circle of Health Study.

European journal of nutrition - 1 Sept 2023

Ilozumba Mmadili N, Yaghjyan Lusine, Datta Susmita, Zhao Jinying, Hong Chi-Chen, Lunetta Kathryn L, Zirpoli Gary, Bandera Elisa V, Palmer Julie R, Yao Song, Ambrosone Christine B, Cheng Ting-Yuan David

Abstract excerpt

BACKGROUND: Excessive energy intake has been shown to affect the mammalian target of the rapamycin (mTOR) signaling pathway and breast cancer risk. It is not well understood whether there are gene-environment interactions between mTOR pathway genes and energy intake in relation to breast cancer risk. METHODS: The study included 1642 Black women (809 incident breast cancer cases and 833 controls) from the Women's...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37209192
DOI: 10.1007/s00394-023-03176-y
PMCID: PMC10695182

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