Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The PTPN22 gene is associated with idiopathic inflammatory myopathy.

Muscle & nerve - 1 Feb 2017

Maundrell Adam, Lester Sue, Rischmueller Maureen, Hill Catherine, Cleland Leslie G, Blumbergs Peter, Wiese Michael, Limaye Vidya

Abstract excerpt

INTRODUCTION: The aim of this study was to determine whether a single-nucleotide polymorphism (SNP; 1858CT, R620W) in the protein tyrosine phosphatase N22 (PTPN22) gene confers susceptibility to idiopathic inflammatory myopathy (IIM) in South Australian patients with IIM. METHODS: Genotyping was performed on stored DNA from 199 patients with histologically confirmed polymyositis (PM), dermatomyositis (DM), and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Australia
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to PTPN22 gene

Share to Genetic Predisposition to Disease

Share to Myositis

Share to Polymorphism, Single Nucleotide

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Source

Identifiers

PMID: 27312665
DOI: 10.1002/mus.25222

Genes

PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The PTPN22 gene is associated with idiopathic inflammatory myopathy.PMID 27312665Read ↗

The protein tyrosine phosphatase N22 gene is associated with juvenile and adult idiopathic inflammatory myopathy independent of the HLA 8.1 haplotype in British Caucasian patients.Semantic proximity Read ↗

Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups.Semantic proximity Read ↗

New developments in genetics of myositis.Semantic proximity Read ↗

The Genetics of Autoimmune MyositisSemantic proximity Read ↗

Association between IL1B rs16944 polymorphism and the risk of idiopathic inflammatory myopathies.Semantic proximity Read ↗

Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1 and -DQA1 allelic profiles and motifs define clinicopathologic groups in caucasians.Semantic proximity Read ↗

Why is PTPN22 a good candidate susceptibility gene for autoimmune disease?Semantic proximity Read ↗

An update on the immunogenetics of idiopathic inflammatory myopathies: major histocompatibility complex and beyond.Semantic proximity Read ↗

Immunoglobulin gene polymorphisms are susceptibility factors in clinical and autoantibody subgroups of the idiopathic inflammatory myopathies.Semantic proximity Read ↗

Immune-Array Analysis in Sporadic Inclusion Body Myositis Reveals HLA-DRB1 Amino Acid Heterogeneity Across the Myositis Spectrum.Semantic proximity Read ↗

Association of the PTPN22*R620W polymorphism with autoimmune myasthenia gravis.Semantic proximity Read ↗

Genetic association study of NF-κB genes in UK Caucasian adult and juvenile onset idiopathic inflammatory myopathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.