Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

New developments in genetics of myositis.

Current opinion in rheumatology - 1 Nov 2016

Rothwell Simon, Lamb Janine A, Chinoy Hector

Abstract excerpt

PURPOSE OF REVIEW: This article reviews the advances that have been made in our understanding of the genetics of the idiopathic inflammatory myopathies (IIM) in the past 2 years, with a particular focus on polymyositis, dermatomyositis and inclusion body myositis. RECENT FINDINGS: Two large human leukocyte antigen (HLA) imputation studies have confirmed a strong association with the 8.1 ancestral haplotype in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune Diseases
Share to Dermatomyositis
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Haplotypes

Share to HLA Antigens

Share to Myositis

Share to Myositis, Inclusion Body

Share to Risk Factors

Source

Identifiers

PMID: 27466937
DOI: 10.1097/BOR.0000000000000328

Genes

BLK
PTPN22
STAT4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

New developments in genetics of myositis.PMID 27466937Read ↗

The Genetics of Autoimmune MyositisSemantic proximity Read ↗

Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups.Semantic proximity Read ↗

Strategies for evaluating idiopathic inflammatory myopathy disease susceptibility genes.Semantic proximity Read ↗

New Developments in the Genetics of Inclusion Body Myositis.Semantic proximity Read ↗

Genetics in inclusion body myositis.Semantic proximity Read ↗

Immune-Array Analysis in Sporadic Inclusion Body Myositis Reveals HLA-DRB1 Amino Acid Heterogeneity Across the Myositis Spectrum.Semantic proximity Read ↗

Risk factors and disease mechanisms in myositis.Semantic proximity Read ↗

Discovery of new myositis genetic associations through leveraging other immune-mediated diseases.Semantic proximity Read ↗

Entering a new phase of immunogenetics in the idiopathic inflammatory myopathies.Semantic proximity Read ↗

Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes.Semantic proximity Read ↗

Identification of Novel Associations and Localization of Signals in Idiopathic Inflammatory Myopathies Using Genome-Wide Imputation.Semantic proximity Read ↗

Immunogenetics of Idiopathic Inflammatory Myopathies: The Role of HLA Genes Within and Beyond the Ancestral Haplotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.