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The Genetics of Autoimmune Myositis

26 May 2022

Abstract excerpt

The idiopathic inflammatory myopathies (IIM) are rare, heterogeneous systemic autoimmune disorders, characterized by inflammation of skeletal muscle and multi-organ involvement. Studies to identify genetic risk factors and dysregulated gene expression in IIM aim to increase our understanding of disease pathogenesis. Genome-wide association studies have confirmed the HLA region as the most strongly associated...

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PMID: 35693792
DOI: 10.3389/fimmu.2022.886290

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