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Article

p63 and p73: Roles in Development and Tumor Formation

1 Jul 2004

Abstract excerpt

The tumor suppressor p53 is critically important in the cellular damage response and is the founding member of a family of proteins. All three genes regulate cell cycle and apoptosis after DNA damage. However, despite a remarkable structural and partly functional similarity among p53, p63, and p73, mouse knockout studies revealed an unexpected functional diversity among them. p63 and p73 knockouts exhibit severe...

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Identifiers

PMID: 15280445
DOI: 10.1158/1541-7786.371.2.7

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Source receipt: pubmed, retrieved 7 Sept 2026.

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