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Article

The Shu complex promotes error-free tolerance of alkylation-induced base excision repair products.

Nucleic acids research - 30 Sept 2016

Godin Stephen K, Zhang Zhuying, Herken Benjamin W, Westmoreland James W, Lee Alison G, Mihalevic Michael J, Yu Zhongxun, Sobol Robert W, Resnick Michael A, Bernstein Kara A

Abstract excerpt

Here, we investigate the role of the budding yeast Shu complex in promoting homologous recombination (HR) upon replication fork damage. We recently found that the Shu complex stimulates Rad51 filament formation during HR through its physical interactions with Rad55-Rad57. Unlike other HR factors, Shu complex mutants are primarily sensitive to replicative stress caused by MMS and not to more direct DNA breaks....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27298254
DOI: 10.1093/nar/gkw535
PMCID: PMC5041462

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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