Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Shu proteins promote the formation of homologous recombination intermediates that are processed by Sgs1-Rmi1-Top3.

Molecular biology of the cell - 1 Oct 2007

Mankouri Hocine W, Ngo Hien-Ping, Hickson Ian D

Abstract excerpt

CSM2, PSY3, SHU1, and SHU2 (collectively referred to as the SHU genes) were identified in Saccharomyces cerevisiae as four genes in the same epistasis group that suppress various sgs1 and top3 mutant phenotypes when mutated. Although the SHU genes have been implicated in homologous recombination repair (HRR), their precise role(s) within this pathway remains poorly understood. Here, we have identified a specific...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Repair
Share to Epistasis, Genetic
Share to Genes, Fungal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hydroxyurea

Share to Methyl Methanesulfonate

Share to Mutant Proteins

Share to Recombination, Genetic

Share to RecQ Helicases

Source

Open in PubMed Open full text

Identifiers

PMID: 17671161
DOI: 10.1091/mbc.e07-05-0490
PMCID: PMC1995734

Genes

RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Shu proteins promote the formation of homologous recombination intermediates that are processed by Sgs1-Rmi1-Top3.PMID 17671161Read ↗

Structural basis for the functional role of the Shu complex in homologous recombination.Semantic proximity Read ↗

The Shu complex interacts with the replicative helicase to prevent mutations and aberrant recombination.Semantic proximity Read ↗

A genetic screen for top3 suppressors in Saccharomyces cerevisiae identifies SHU1, SHU2, PSY3 and CSM2: four genes involved in error-free DNA repair.Semantic proximity Read ↗

The Shu complex promotes error-free tolerance of alkylation-induced base excision repair products.Semantic proximity Read ↗

Processing of homologous recombination repair intermediates by the Sgs1-Top3-Rmi1 and Mus81-Mms4 complexesSemantic proximity Read ↗

Yeast Rmi1/Nce4 controls genome stability as a subunit of the Sgs1-Top3 complex.Semantic proximity Read ↗

Sgs1 function in the repair of DNA replication intermediates is separable from its role in homologous recombinational repair.Semantic proximity Read ↗

Effects of mutations in SGS1 and in genes functionally related to SGS1 on inverted repeat-stimulated spontaneous unequal sister-chromatid exchange in yeast.Semantic proximity Read ↗

Sgs1 Binding to Rad51 Stimulates Homology-Directed DNA Repair in Saccharomyces cerevisiae.Semantic proximity Read ↗

The Shu Complex Prevents Mutagenesis and Cytotoxicity of Single-Strand Specific Alkylation LesionsSemantic proximity Read ↗

The ability of Sgs1 to interact with DNA topoisomerase III is essential for damage-induced recombination.Semantic proximity Read ↗

Involvement of SGS1 in DNA damage-induced heteroallelic recombination that requires RAD52 in Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.