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Article

Structural basis for the functional role of the Shu complex in homologous recombination.

Nucleic acids research - 15 Dec 2017

Zhang Shicheng, Wang Linlin, Tao Ye, Bai Tuya, Lu Rong, Zhang Tianlong, Chen Jiangye, Ding Jianping

Abstract excerpt

The Shu complex, a conserved regulator consisting of Csm2, Psy3, Shu1 and Shu2 in budding yeast, plays an important role in the assembly of the Rad51-ssDNA filament in homologous recombination. However, the molecular basis for the assembly of the Shu complex and its functional role in DNA repair is still elusive. Here, we report the crystal structure of the yeast Shu complex, revealing that Csm2, Psy3, Shu1 and...

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Identifiers

PMID: 29069504
DOI: 10.1093/nar/gkx992
PMCID: PMC5727457

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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