Article
Polymorphisms of CHAT but not TFAM or VR22 are Associated with Alzheimer Disease Risk.
Medical science monitor : international medical journal of experimental and clinical research - 7 Jun 2016
Gao Lili, Zhang Yan, Deng Jinghua, Yu Wenbing, Yu Yunxia
Abstract excerpt
BACKGROUND Alzheimer disease (AD) is a chronic neurodegenerative disease that is one of the most prevalent health problems among seniors. The cause of AD has not yet been elucidated, but many risk factors have been identified that might contribute to the pathogenesis and prognosis of AD. We conducted a meta-analysis of studies involving CHAT, TFAM, and VR22 polymorphisms and AD susceptibility to further...
Topics
- Aged
- Aged, 80 and over
- Alzheimer Disease
- Apolipoproteins E
- Case-Control Studies
- Choline O-Acetyltransferase
- DNA-Binding Proteins
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Humans
- Male
- Middle Aged
- Mitochondrial Proteins