Article
Association of rs2062323 in the TREM1 gene with Alzheimer's disease and cerebrospinal fluid-soluble TREM2.
CNS neuroscience & therapeutics - 1 Jun 2023
Wang Zuo-Teng, Fu Yan, Chen Shi-Dong, Huang Yu-Yuan, Ma Ya-Hui, Wang Yan-Jiang, Tan Lan, Yu Jin-Tai
Abstract excerpt
INTRODUCTION AND AIMS: Genetic variations play a significant role in determining an individual's AD susceptibility. Research on the connection between AD and TREM1 gene polymorphisms (SNPs) remained lacking. We sought to examine the associations between TREM1 SNPs and AD. METHODS: Based on the 1000 Genomes Project data, linkage disequilibrium (LD) analyses were utilized to screen for candidate SNPs in the TREM1...
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