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Article

Choline acetyltransferase 2384G>a polymorphism and the risk of Alzheimer disease.

Alzheimer disease and associated disorders - 1 Jan 2000

Lee Jung Jae, Jo Sangmee Ahn, Park Joon Hyuk, Lee Seok Bum, Jo Inho, Kim Do Kwan, Huh Yoonseok, Youn Jong Chul, Jhoo Jin Hyeong, Park Koung Un, Park Sung Sup, Lee Dong Young, Woo Jong Inn, Kim Ki Woong

Abstract excerpt

The potential association between choline acetyltransferase (CHAT) polymorphism and the risk of Alzheimer disease (AD) has been controversial. We examined the main effect of CHAT polymorphism and its interaction with apolipoprotein E (APOE) polymorphism in the development of AD in a well-powered elderly Korean sample. We analyzed CHAT 2384G>A polymorphism and APOE polymorphism among 736 Korean patients with...

Topics

Age of Onset
Aged
Aged, 80 and over
Alleles
Alzheimer Disease
Apolipoproteins E
Asian People
Choline O-Acetyltransferase
Female
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Testing

Genotype

Humans

Logistic Models

Male

Middle Aged

Odds Ratio

Polymorphism, Genetic

Source

Identifiers

PMID: 21602657
DOI: 10.1097/WAD.0b013e31821cbcaf

Genes

CHAT
APOE

Provenance

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