Article
Association of Choline Acetyltransferase Gene Polymorphisms (SNPs rs868750G/A, rs1880676G/A, rs2177369G/A and rs3810950G/A) with Alzheimer's Disease Risk: A Meta-Analysis.
PloS one - 1 Jan 2016
Yuan Hai, Xia Qing, Ling Kang, Wang Xiaotong, Wang Xiumin, Du Xunping
Abstract excerpt
BACKGROUND: Epidemiological studies have investigated the role of choline acetyltransferase (ChAT) in Alzheimer's disease (AD). ChAT gene polymorphisms (SNPs rs868750G/A, rs1880676G/A, rs2177369G/A, and rs3810950G/A) may be associated with the risk of AD. In this meta-analysis, we determined the relationship between the four polymorphisms and the risk of AD. METHODS: We searched MEDLINE, EMBASE, and HuGEnet...
Topics
- Alzheimer Disease
- Asian People
- Choline O-Acetyltransferase
- Female
- Genetic Predisposition to Disease
- Humans
- MEDLINE
- Male
- Polymorphism, Single Nucleotide
- Risk Factors