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Article

Association of CHAT Gene Polymorphism rs3793790 and rs2177370 with Donepezil Response and the Risk of Alzheimer's Disease Continuum.

Clinical interventions in aging - 1 Jan 2024

Sun Hongmei, Lv Chao, Zhang Xiaoxue, Sun Xuan, Chen Siyu, Li Ke, Hu Yazhuo, Feng Yuxin, Yin Tong, Jia Jianjun

Abstract excerpt

Background: Genetic variation plays an important role in drug response, there are few relevant studies on patients with Alzheimer's disease continuum (ADC). Objective: This study focused on the associations between two single nucleotide polymorphisms (SNPs) (rs3793790 and rs2177370) located in the CHAT gene and donepezil response in ADC patients, and further evaluated the associations between the two SNPs and...

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Identifiers

PMID: 38894884
DOI: 10.2147/CIA.S462786
PMCID: PMC11182730

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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