Article
Pharmacogenetics of nevirapine excretion into breast milk and infants' exposure through breast milk versus postexposure prophylaxis.
Pharmacogenomics - 1 Jun 2016
Olagunju Adeniyi, Khoo Saye, Owen Andrew
Abstract excerpt
AIM: The influence of genetic factors on nevirapine (NVP) breast milk pharmacokinetics and breastfed infants' exposure were investigated. PATIENTS & METHODS: Associations between nine SNPs in NVP disposition genes in mothers and its plasma and breast milk concentrations were explored in nursing mother-infant pairs. RESULTS: NVP pharmacokinetics in maternal plasma, breast milk and infant exposure indices were...
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