Article
Impact of maternal and infant antiretroviral drug regimens on drug resistance in HIV-infected breastfeeding infants.
The Pediatric infectious disease journal - 1 Apr 2013
Fogel Jessica M, Mwatha Anthony, Richardson Paul, Brown Elizabeth R, Chipato Tsungai, Alexandre Michel, Moodley Dhayendre, Elbireer Ali, Mirochnick Mark, George Kathleen, Mofenson Lynne M, Zwerski Sheryl, Coovadia Hoosen M, Eshleman Susan H
Abstract excerpt
BACKGROUND: The HIV Prevention Trials Network (HPTN) 046 trial evaluated the efficacy of extended infant nevirapine (NVP) administration for prevention of HIV transmission through breastfeeding. Infants received daily NVP up to 6 weeks of age. HIV-uninfected infants (the intent-to-treat group) received daily NVP or placebo up to 6 months of age. We analyzed emergence of NVP resistance in infants who acquired HIV...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.