Article
Pharmacogenetic predictors of nevirapine pharmacokinetics in Ghanaian children living with HIV with or without TB coinfection.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Aug 2021
Langaee Taimour, Al-Shaer Mohammad H, Gong Yan, Lima Elizabeth, Antwi Sampson, Enimil Anthony, Dompreh Albert, Yang Hongmei, Alghamdi Wael A, Wiesner Lubbe, Peloquin Charles A, Kwara Awewura
Abstract excerpt
Nevirapine (NVP) is a non-nucleoside reverse transcriptase inhibitor that is used in the treatment of human immunodeficiency virus (HIV) infection in children younger than 3 years old. Identifying genetic predictors of NVP pharmacokinetics (PK) in young children is important because inter-individual variability in NVP concentrations contributes to variable treatment response and the information may be used to...
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