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Article

Integration of absorption, distribution, metabolism, and elimination genotyping data into a population pharmacokinetic analysis of nevirapine.

Pharmacogenetics and genomics - 1 Nov 2011

Lehr Thorsten, Yuan Jing, Hall David, Zimdahl-Gelling Heike, Schaefer Hans Guenter, Staab Alexander, MacGregor Thomas R, Jayadev Supriya

Abstract excerpt

OBJECTIVES: The aim of this analysis was to show the applicability of a newly developed algorithm to assess the influence of genetic variants and other covariates on nevirapine's drug disposition. The algorithm combines high-throughput genotyping data and nonlinear mixed effects modeling methods....

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Identifiers

PMID: 21860339
DOI: 10.1097/FPC.0b013e32834a522e

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21860339-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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