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Article

Emergence and persistence of nevirapine resistance in breast milk after single-dose nevirapine administration.

AIDS (London, England) - 20 Feb 2010

Hudelson Sarah E, McConnell Michelle S, Bagenda Danstan, Piwowar-Manning Estelle, Parsons Teresa L, Nolan Monica L, Bakaki Paul M, Thigpen Michael C, Mubiru Michael, Fowler Mary Glenn, Eshleman Susan H

Abstract excerpt

OBJECTIVE: Single-dose nevirapine (NVP) (sdNVP) can reduce the risk of HIV vertical transmission. We assessed risk factors for NVP resistance in plasma and breast milk from sdNVP-exposed Ugandan women. METHODS: Samples were analyzed using the Roche AMPLICOR HIV-1 Monitor Test Kit, version 1.5, and the ViroSeq HIV-1 Genotyping System. NVP concentrations were determined by liquid chromatography with tandem mass...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20057308
DOI: 10.1097/QAD.0b013e3283346e60
PMCID: PMC3065236

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