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Article

Nevirapine resistance and breast-milk HIV transmission: effects of single and extended-dose nevirapine prophylaxis in subtype C HIV-infected infants.

PloS one - 1 Jan 2009

Moorthy Anitha, Gupta Amita, Bhosale Ramesh, Tripathy Srikanth, Sastry Jayagowri, Kulkarni Smita, Thakar Madhuri, Bharadwaj Renu, Kagal Anju, Bhore Arvind V, Patil Sandesh, Kulkarni Vandana, Venkataramani Varadharajan, Balasubramaniam Usha, Suryavanshi Nishi, Ziemniak Carrie, Gupte Nikhil, Bollinger Robert, Persaud Deborah

Abstract excerpt

BACKGROUND: Daily nevirapine (NVP) prophylaxis to HIV-exposed infants significantly reduces breast-milk HIV transmission. We assessed NVP-resistance in Indian infants enrolled in the "six-week extended-dose nevirapine" (SWEN) trial who received single-dose NVP (SD-NVP) or SWEN for prevention of breast-milk HIV transmission but who also acquired subtype C HIV infection during the first year of life....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19119321
DOI: 10.1371/journal.pone.0004096
PMCID: PMC2606064

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