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Article

Effect of VKORC1, CYP2C9, CFP4F2, and GGCX Gene Polymorphisms on Warfarin Dose in Japanese Pediatric Patients.

Molecular diagnosis & therapy - 1 Aug 2016

Wakamiya Takuya, Hokosaki Tatsunori, Tsujimoto Shin-Ichi, Kadota Keisuke, Nakano Yusuke, Watanabe Shigeo, Iwamoto Mari, Yanagimachi Masakatsu, Ito Shuichi

Abstract excerpt

BACKGROUND: Warfarin dosage requirements show considerable inter-individual variability. There are some reports of warfarin dose regimens correlating with single nucleotide polymorphisms (SNP) for CYP2C9, VKORC1 and other genes in adults. In children, however, reports are scarcer than in adults and the number of genes examined is more limited. We explored the effects of genetic variation on warfarin dose...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27262824
DOI: 10.1007/s40291-016-0212-5

Genes

VKORC1
GGCX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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