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Article

The effect of CYP2C9 and VKORC1 genetic polymorphisms on warfarin dose requirements in a pediatric population.

Anatolian journal of cardiology - 1 Oct 2016

Dilge Taşkın Birce, Kula Serdar, Ergün Mehmet Ali, Altun Demet, Olguntürk Rana, Tunaoğlu Fatma Sedef, Oğuz Ayşe Deniz, Gürsel Türkiz

Abstract excerpt

OBJECTIVE: The aim was to investigate the frequency of genetic polymorphisms of cytochrome P4502C9 (CYP2C9) and vitamin K epoxide reductase complex subunit1 (VKORC1) and determine the effect of these polymorphisms on warfarin dose requirements in pediatric patients. METHODS: Fifty-eight pediatric patients with cardiac disease, thrombophilia, or other conditions, taking a stable warfarin dose, aged 0.2-18 years,...

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Source

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Identifiers

PMID: 27182616
DOI: 10.14744/AnatolJCardiol.2015.6150
PMCID: PMC5324942

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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