Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of Metal-Dependent Regulation of ESX-3 Secretion in Intracellular Survival of Mycobacterium tuberculosis

1 Jun 2016

Abstract excerpt

More people die every year from Mycobacterium tuberculosis infection than from infection by any other bacterial pathogen. Type VII secretion systems (T7SS) are used by both environmental and pathogenic mycobacteria to secrete proteins across their complex cell envelope. In the nonpathogen Mycobacterium smegmatis, the ESX-1 T7SS plays a role in conjugation, and the ESX-3 T7SS is involved in metal homeostasis. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibiotic Resistance in Bacteria
Share to Mycobacterium research and diagnosis
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27245412
DOI: 10.1128/iai.00197-16

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of Metal-Dependent Regulation of ESX-3 Secretion in Intracellular Survival of Mycobacterium tuberculosisPMID 27245412Read ↗

The ESX-3 secretion system is necessary for iron and zinc homeostasis in Mycobacterium tuberculosis.Semantic proximity Read ↗

Separable roles for Mycobacterium tuberculosis ESX-3 effectors in iron acquisition and virulence.Semantic proximity Read ↗

Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition.Semantic proximity Read ↗

Mycobacterial Esx-3 Requires Multiple Components for Iron AcquisitionSemantic proximity Read ↗

ESX secretion system: The gatekeepers of mycobacterial survivability and pathogenesisSemantic proximity Read ↗

Role of the Mycobacterium tuberculosis ESX-4 Secretion System in Heme Iron Utilization and Pore Formation by PPE ProteinsSemantic proximity Read ↗

ESX-5 Deletions in <i>Mycobacterium tuberculosis</i> Alter Macrophage Cytokine Signaling and Bacterial Heavy Metal ResponseSemantic proximity Read ↗

Characterization of a Mycobacterium tuberculosis ESX-3 conditional mutant: essentiality and rescue by iron and zinc.Semantic proximity Read ↗

The regulatory functions of ESX-1 substrates, EspE and EspF, are separable from secretionSemantic proximity Read ↗

Master control of protein secretion by <i>Mycobacterium tuberculosis</i>Semantic proximity Read ↗

Comprehensive analysis of iron utilization by Mycobacterium tuberculosis.Semantic proximity Read ↗

Lipid metabolism and Type VII secretion systems dominate the genome scale virulence profile of Mycobacterium tuberculosis in human dendritic cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.