Article

Master control of protein secretion by <i>Mycobacterium tuberculosis</i>

2025-03-13

Abstract excerpt

<h4>ABSTRACT</h4> Tuberculosis is the leading cause of death from a single infectious disease. Mycobacterium tuberculosis secretes proteins using five ESX systems with distinctive functions essential for its growth and virulence. Here we show that a non-canonical supercomplex of the EsxU-EsxT proteins, encoded in the esx-4 locus, with the orphan EsxE-EsxF proteins, encoded in the cpnT operon, is required for t...

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Literature Corpus work: 693b2a9a-e9f4-59a8-a360-b39f91ea18bb
DOI: 10.1101/2025.03.13.643117

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