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Article

The ESX-3 secretion system is necessary for iron and zinc homeostasis in Mycobacterium tuberculosis.

PloS one - 1 Jan 2013

Serafini Agnese, Pisu Davide, Palù Giorgio, Rodriguez G Marcela, Manganelli Riccardo

Abstract excerpt

ESX-3 is one of the five type VII secretion systems encoded by the Mycobacterium tuberculosis genome. We recently showed the essentiality of ESX-3 for M. tuberculosis viability and proposed its involvement in iron and zinc metabolism. In this study we confirmed the role of ESX-3 in iron uptake an...

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Identifiers

PMID: 24155985
DOI: 10.1371/journal.pone.0078351
PMCID: PMC3796483

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24155985-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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