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Article

HLA-DRB*1501 associations with magnetic resonance imaging measures of grey matter pathology in multiple sclerosis.

Multiple sclerosis and related disorders - 1 May 2016

Yaldizli Özgür, Sethi Varun, Pardini Matteo, Tur Carmen, Mok Kin Y, Muhlert Nils, Liu Zheng, Samson Rebecca S, Wheeler-Kingshott Claudia A M, Yousry Tarek A, Houlden Henry, Hardy John, Miller David H, Chard Declan T

Abstract excerpt

BACKGROUND: The HLA-DRB*1501 haplotype influences the risk of developing multiple sclerosis (MS), but it is not known how it affects grey matter pathology. AIM: To assess HLA-DRB(*)1501 effects on magnetic resonance imaging (MRI) cortical grey matter pathology. METHODS: Whole and lesional cortical grey matter volumes, lesional and normal-appearing grey matter magnetization transfer ratio were measured in 85...

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PMID: 27237756
DOI: 10.1016/j.msard.2016.03.003

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