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Article

HLA DRB1*1501 is only modestly associated with lesion burden at the first demyelinating event.

Journal of neuroimmunology - 1 Jul 2011

Horakova Dana, Zivadinov Robert, Weinstock-Guttman Bianca, Havrdova Eva, Tamaño-Blanco Miriam, Tyblova Michaela, Hussein Sara, Bergsland Niels, Willis Laura, Krasensky Jan, Vaneckova Manuela, Seidl Zdenek, Lelkova Petra, Ramanathan Murali

Abstract excerpt

OBJECTIVES: The presence of MRI lesions at the first demyelinating event increases the risk of developing clinically definite multiple sclerosis (MS). The HLA DRB1*1501 genotype is linked to MS susceptibility but its relationship to quantitative MRI parameters at the first demyelinating event has not been assessed. The objectives were to assess the associations between HLA DRB1*1501 status and magnetic resonance...

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PMID: 21621859
DOI: 10.1016/j.jneuroim.2011.04.011

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