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Article

HLA-DRB1*1501 and spinal cord magnetic resonance imaging lesions in multiple sclerosis.

Archives of neurology - 1 Dec 2009

Sombekke Madeleine H, Lukas Carsten, Crusius J Bart A, Tejedor Diego, Killestein Joep, Arteta David, Martínez Antonio, Uitdehaag Bernard M J, Knol Dirk L, Peña A Salvador, Geurts Jeroen J G, De Jager Philip L, Barkhof Frederik, Vrenken Hugo, Polman Chris H

Abstract excerpt

BACKGROUND: Multiple sclerosis (MS) is a heterogeneous neurologic disease with extensive variation with respect to the most affected central nervous system region (brain vs spinal cord). OBJECTIVE: To test the hypothesis that this variation in lesion location (brain vs spinal cord) might be (partially) genetically determined. DESIGN: Candidate gene study. SETTING: Academic research. PATIENTS: Patients were...

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Identifiers

PMID: 20008659
DOI: 10.1001/archneurol.2009.278

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