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Article

Detecting Gene-Environment Interactions for a Quantitative Trait in a Genome-Wide Association Study.

Genetic epidemiology - 1 Jul 2016

Zhang Pingye, Lewinger Juan Pablo, Conti David, Morrison John L, Gauderman W James

Abstract excerpt

A genome-wide association study (GWAS) typically is focused on detecting marginal genetic effects. However, many complex traits are likely to be the result of the interplay of genes and environmental factors. These SNPs may have a weak marginal effect and thus unlikely to be detected from a scan of marginal effects, but may be detectable in a gene-environment (G × E) interaction analysis. However, a genome-wide...

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Identifiers

PMID: 27230133
DOI: 10.1002/gepi.21977
PMCID: PMC5108681

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MARCO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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