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Article

Finding novel genes by testing G × E interactions in a genome-wide association study.

Genetic epidemiology - 1 Sept 2013

Gauderman W James, Zhang Pingye, Morrison John L, Lewinger Juan Pablo

Abstract excerpt

In a genome-wide association study (GWAS), investigators typically focus their primary analysis on the direct (marginal) associations of each single nucleotide polymorphism (SNP) with the trait. Some SNPs that are truly associated with the trait may not be identified in this scan if they have a weak marginal effect and thus low power to be detected. However, these SNPs may be quite important in subgroups of the...

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Identifiers

PMID: 23873611
DOI: 10.1002/gepi.21748
PMCID: PMC4348012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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