Article
Rapid testing of gene-gene interactions in genome-wide association studies of binary and quantitative phenotypes.
Genetic epidemiology - 1 Dec 2011
Bhattacharya Kanishka, McCarthy Mark I, Morris Andrew P
Abstract excerpt
Genome-wide association (GWA) studies have been extremely successful in identifying novel loci contributing effects to a wide range of complex human traits. However, despite this success, the joint marginal effects of these loci account for only a small proportion of the heritability of these tra...
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