Article
Genome-wide meta-analysis of joint tests for genetic and gene-environment interaction effects.
Human heredity - 1 Jan 2010
Aschard Hugues, Hancock Dana B, London Stephanie J, Kraft Peter
Abstract excerpt
BACKGROUND: There is growing interest in the study of gene-environment interactions in the context of genome-wide association studies (GWASs). These studies will likely require meta-analytic approaches to have sufficient power. METHODS: We describe an approach for meta-analysis of a joint test for genetic main effects and gene-environment interaction effects. Using simulation studies based on a meta-analysis of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
