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Article

Gene-environment interaction in genome-wide association studies.

American journal of epidemiology - 15 Jan 2009

Murcray Cassandra E, Lewinger Juan Pablo, Gauderman W James

Abstract excerpt

It is a commonly held belief that most complex diseases (e.g., diabetes, asthma, cancer) are affected in part by interactions between genes and environmental factors. However, investigators conducting genome-wide association studies typically test for only the marginal effects of each genetic marker on disease. In this paper, the authors propose an efficient and easily implemented 2-step analysis of genome-wide...

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Identifiers

PMID: 19022827
DOI: 10.1093/aje/kwn353
PMCID: PMC2732981

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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