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Article

Human mutations affect the epigenetic/bookmarking function of HNF1B.

Nucleic acids research - 30 Sept 2016

Lerner Jonathan, Bagattin Alessia, Verdeguer Francisco, Makinistoglu Munevver P, Garbay Serge, Felix Tristan, Heidet Laurence, Pontoglio Marco

Abstract excerpt

Bookmarking factors are transcriptional regulators involved in the mitotic transmission of epigenetic information via their ability to remain associated with mitotic chromatin. The mechanisms through which bookmarking factors bind to mitotic chromatin remain poorly understood. HNF1β is a bookmarking transcription factor that is frequently mutated in patients suffering from renal multicystic dysplasia and...

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Identifiers

PMID: 27229139
DOI: 10.1093/nar/gkw467
PMCID: PMC5041451

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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